Skip to Content
MilliporeSigma

MED23

mediator complex subunit 23

Synonyms:
ARC130, CRSP130, CRSP133, CRSP3, DRIP130, MRT18, SUR-2, SUR2
Species:
UniProtKB ID:
Gene ID:
  • Human(9439) Summary: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012]
  • Mouse(70208) mediator complex subunit 23
  • Rat(309565) mediator complex subunit 23
  • dog(474822) mediator complex subunit 23
  • domestic cat(101093861) mediator complex subunit 23
  • Zebrafish(445483) mediator complex subunit 23
  • fruit fly(37639) Mediator complex subunit 23
  • chicken(426927) mediator complex subunit 23
  • naked mole-rat(101704535) mediator complex subunit 23
  • domestic guinea pig(100727487) mediator complex subunit 23
  • Domestic Rabbit(100342894) mediator complex subunit 23
  • Horse(100067556) mediator complex subunit 23
  • sheep(101121942) mediator complex subunit 23
  • cow(513610) mediator complex subunit 23

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MED23, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, guinea pig, horse, human, mouse, rabbit, rat, yeast
Application
western blot
Anti-MED23 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Monoclonal Anti-CRSP3 antibody produced in mouse, clone 4H6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MED23,
Species
human
MISSION® esiRNA, targeting mouse Med23,
Species
mouse