Skip to Content
MilliporeSigma

ME2

malic enzyme 2, NAD(+)-dependent, mitochondrial

Synonyms:
ODS1
Species:
UniProtKB ID:
Gene ID:
  • Human(4200) Summary: This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009]
  • Mouse(107029) malic enzyme 2, NAD(+)-dependent, mitochondrial
  • Rat(307270) malic enzyme 2, NAD(+)-dependent, mitochondrial
  • Zebrafish(445233) malic enzyme 2, NAD(+)-dependent, mitochondrial
  • dog(476198) malic enzyme 2, NAD(+)-dependent, mitochondrial
  • domestic cat(101092963) malic enzyme 2, NAD(+)-dependent, mitochondrial
  • Horse(100069637) malic enzyme 2, NAD(+)-dependent, mitochondrial
  • cow(507817) malic enzyme 2, NAD(+)-dependent, mitochondrial
  • sheep(101117980) malic enzyme 2, NAD(+)-dependent, mitochondrial
  • domestic guinea pig(100720540) malic enzyme 2, NAD(+)-dependent, mitochondrial
  • naked mole-rat(101702791) malic enzyme 2, NAD(+)-dependent, mitochondrial

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ME2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ME2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Me2,
Species
mouse
MISSION® esiRNA, targeting human ME2,
Species
human
MISSION® esiRNA, targeting mouse Me2,
Species
mouse