MCM7
minichromosome maintenance complex component 7
Synonyms:
CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146
Species:
Human MCM7 (4176), Mouse Mcm7 (17220), Rat Mcm7 (288532), fruit fly Mcm7 (39014), Zebrafish mcm7 (192333), dog MCM7 (479737), domestic cat MCM7 (101088383), Horse MCM7 (100053690), cow MCM7 (539924), sheep MCM7 (101108015) ...More
UniProtKB ID:
Gene ID:
- Human(4176) Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(17220) minichromosome maintenance deficient 7 (S. cerevisiae)
- Rat(288532) minichromosome maintenance complex component 7
- fruit fly(39014) Minichromosome maintenance 7
- Zebrafish(192333) MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)
- dog(479737) minichromosome maintenance complex component 7
- domestic cat(101088383) minichromosome maintenance complex component 7
- Horse(100053690) minichromosome maintenance complex component 7
- cow(539924) minichromosome maintenance complex component 7
- sheep(101108015) minichromosome maintenance complex component 7
- Domestic Rabbit(100337896) minichromosome maintenance complex component 7
- naked mole-rat(101724967) minichromosome maintenance complex component 7
- domestic guinea pig(100719227) minichromosome maintenance complex component 7
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MCM7 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-MCM7 Antibody, from rabbit,
Species Reactivity
chimpanzee, human, rat, rhesus macaque
Application
western blot
Anti-MCM7 Antibody, clone 1C20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-MCM7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-MCM7 antibody produced in mouse, clone 6C2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot