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Merck

MBD4

methyl-CpG binding domain protein 4

Synonyms:
MED1
Species:
Human MBD4 (8930), Mouse Mbd4 (17193), Rat Mbd4 (680915), Domestic Rabbit MBD4 (100339392), sheep MBD4 (101102431), naked mole-rat Mbd4 (101724783), domestic guinea pig Mbd4 (100715374), cow MBD4 (511463), Thale Cress MBD4 (825478), chicken MBD4 (395428) ...More
UniProtKB ID:
O95243, D3DNC3, D3DNC4, Q2MD36, Q7Z4T3, Q96F09
Gene ID:
  • Human(8930) Summary: The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
  • Mouse(17193) methyl-CpG binding domain protein 4
  • Rat(680915) methyl-CpG binding domain protein 4
  • Domestic Rabbit(100339392) methyl-CpG binding domain protein 4
  • sheep(101102431) methyl-CpG binding domain protein 4
  • naked mole-rat(101724783) methyl-CpG binding domain protein 4
  • domestic guinea pig(100715374) methyl-CpG binding domain protein 4
  • cow(511463) methyl-CpG binding domain protein 4
  • Thale Cress(825478) methyl-CpG-binding domain-containing protein 4
  • chicken(395428) methyl-CpG binding domain protein 4
  • Horse(100056679) methyl-CpG binding domain protein 4
  • domestic cat(101097799) methyl-CpG binding domain protein 4
  • dog(100684130) methyl-CpG binding domain protein 4
  • Zebrafish(399691) methyl-CpG binding domain protein 4

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA002031
Anti-MBD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EMU057211
MISSION® esiRNA, targeting mouse Mbd4,
Species
mouse
EHU025861
MISSION® esiRNA, targeting human MBD4,
Species
human