MAFK
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
Synonyms:
NFE2U, P18
Species:
Human MAFK (7975), Mouse Mafk (17135), Rat Mafk (246760), dog MAFK (100685400), domestic guinea pig Mafk (100735555), chicken MAFK (395518), Zebrafish mafk (415133), domestic cat MAFK (101089820), naked mole-rat Mafk (101707776), cow MAFK (618914)
UniProtKB ID:
Gene ID:
- Human(7975) Summary: The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM, Nov 2008]
- Mouse(17135) v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)
- Rat(246760) v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
- dog(100685400) v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
- domestic guinea pig(100735555) v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
- chicken(395518) v-maf musculoaponeurotic fibrosarcoma oncogene homolog K
- Zebrafish(415133) v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
- domestic cat(101089820) v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
- naked mole-rat(101707776) v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
- cow(618914) v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MAFK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-MafK/Nfe2u Antibody, serum, from rabbit,
Species Reactivity
human, mouse, rat
Application
ChIP
electrophoretic mobility shift assay
western blot
electrophoretic mobility shift assay
western blot
Anti-MAFK (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MAFK antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
guinea pig, human, mouse, rat
Application
western blot
esiRNA
Product Number
Description
Species