MADD
MAP-kinase activating death domain
Synonyms:
DENN, IG20, RAB3GEP
Species:
Human MADD (8567), Mouse Madd (228355), Rat Madd (94193), sheep MADD (101117276), domestic guinea pig Madd (100725450), naked mole-rat Madd (101710698), cow MADD (534306), Horse MADD (100051327), domestic cat MADD (101093297), dog MADD (475982) ...More
UniProtKB ID:
Gene ID:
- Human(8567) Summary: Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Mouse(228355) MAP-kinase activating death domain
- Rat(94193) MAP-kinase activating death domain
- sheep(101117276) MAP-kinase activating death domain
- domestic guinea pig(100725450) MAP-kinase activating death domain
- naked mole-rat(101710698) MAP-kinase activating death domain
- cow(534306) MAP-kinase activating death domain
- Horse(100051327) MAP-kinase activating death domain
- domestic cat(101093297) MAP-kinase activating death domain
- dog(475982) MAP-kinase activating death domain
- chicken(423184) MAP-kinase activating death domain
- Zebrafish(100150917) MAP-kinase activating death domain
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MADD antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunocytochemistry
immunofluorescence
western blot
immunocytochemistry
immunofluorescence
western blot
Anti-MADD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry