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MilliporeSigma

KIAA0196

KIAA0196

Synonyms:
SPG8
Species:
UniProtKB ID:
Gene ID:
  • Human(9897) Summary: This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin-repeat-containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts. More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases. [provided by RefSeq, Aug 2009]
  • dog(475095) KIAA0196 ortholog
  • domestic cat(101090992) KIAA0196 ortholog
  • cow(508040) KIAA0196 ortholog
  • sheep(101104670) KIAA0196 ortholog
  • domestic guinea pig(100725103) KIAA0196 ortholog
  • naked mole-rat(101708947) KIAA0196 ortholog
  • chicken(420334) KIAA0196

Custom & Knockdown Gene Products

  • siRNA

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  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KIAA0196 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-WASHC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-WASHC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Monoclonal Anti-Strumpellin antibody produced in mouse, clone St-1, purified from hybridoma cell culture,
Species Reactivity
human, mouse, rat
Application
flow cytometry
immunoprecipitation (IP)

western blot