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Merck

ITPKA

inositol-trisphosphate 3-kinase A

Synonyms:
IP3-3KA, IP3KA
Species:
Human ITPKA (3706), Mouse Itpka (228550), Rat Itpka (81677), Zebrafish itpka (368717), sheep ITPKA (101115627), dog ITPKA (487507), naked mole-rat Itpka (101698565), chicken ITPKA (395694), cow ITPKA (615813), domestic guinea pig Itpka (100733156)
UniProtKB ID:
P23677, Q8TAN3
Gene ID:
  • Human(3706) Summary: Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011]
  • Mouse(228550) inositol 1,4,5-trisphosphate 3-kinase A
  • Rat(81677) inositol-trisphosphate 3-kinase A
  • Zebrafish(368717) inositol 1,4,5-trisphosphate 3-kinase A
  • sheep(101115627) inositol-trisphosphate 3-kinase A
  • dog(487507) inositol-trisphosphate 3-kinase A
  • naked mole-rat(101698565) inositol-trisphosphate 3-kinase A
  • chicken(395694) inositol 1,4,5-trisphosphate 3-kinase A
  • cow(615813) inositol-trisphosphate 3-kinase A
  • domestic guinea pig(100733156) inositol-trisphosphate 3-kinase A
  • domestic cat(101084366) inositol-trisphosphate 3-kinase A

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA040454
Anti-ITPKA antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
SAB4501592
Anti-IP3KA antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
EHU014771
MISSION® esiRNA, targeting human ITPKA,
Species
human
EMU072601
MISSION® esiRNA, targeting mouse Itpka,
Species
mouse