ITM2B
integral membrane protein 2B
Synonyms:
ABRI, BRI, BRI2, BRICD2B, E25B, E3-16, FBD, imBRI2
Species:
Human ITM2B (9445), Mouse Itm2b (16432), Rat Itm2b (290364), chicken ITM2B (395969), naked mole-rat Itm2b (101704426), domestic guinea pig Itm2b (100716017), sheep ITM2B (100174988), cow ITM2B (510575), dog ITM2B (476916)
UniProtKB ID:
Gene ID:
- Human(9445) Summary: Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq, Oct 2009]
- Mouse(16432) integral membrane protein 2B
- Rat(290364) integral membrane protein 2B
- chicken(395969) integral membrane protein 2B
- naked mole-rat(101704426) integral membrane protein 2B
- domestic guinea pig(100716017) integral membrane protein 2B
- sheep(100174988) integral membrane protein 2B
- cow(510575) integral membrane protein 2B
- dog(476916) integral membrane protein 2B
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ITM2B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-ITM2B antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-ITM2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Monoclonal Anti-ITM2B antibody produced in mouse, clone 1A10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-ITM2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence