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MilliporeSigma

ISCU

iron-sulfur cluster assembly enzyme

Synonyms:
2310020H20Rik, HML, ISU2, NIFU, NIFUN, hnifU
Species:
UniProtKB ID:
Gene ID:
  • Human(23479) Summary: Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. [provided by RefSeq, Jul 2008]
  • Mouse(66383) IscU iron-sulfur cluster scaffold homolog (E. coli)
  • Rat(288740) iron-sulfur cluster scaffold homolog (E. coli)
  • cow(514789) iron-sulfur cluster scaffold homolog (E. coli)
  • chicken(416891) iron-sulfur cluster scaffold homolog (E. coli)
  • naked mole-rat(101713201) iron-sulfur cluster scaffold homolog (E. coli)
  • sheep(101103093) iron-sulfur cluster scaffold homolog (E. coli)
  • dog(477527) iron-sulfur cluster scaffold homolog (E. coli)
  • domestic cat(101088192) iron-sulfur cluster scaffold homolog (E. coli)
  • domestic guinea pig(100724516) iron-sulfur cluster scaffold homolog (E. coli)

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ISCU antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-ISCU antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Monoclonal Anti-NIFUN antibody produced in mouse, clone 3B8-1C4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Iscu,
Species
mouse