Skip to Content
MilliporeSigma

IQSEC2

IQ motif and Sec7 domain 2

Synonyms:
BRAG1, MRX1
Species:
UniProtKB ID:
Gene ID:
  • Human(23096) Summary: This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(245666) IQ motif and Sec7 domain 2
  • Rat(685244) IQ motif and Sec7 domain 2
  • dog(491895) IQ motif and Sec7 domain 2
  • domestic cat(101091849) IQ motif and Sec7 domain 2
  • Horse(100060269) IQ motif and Sec7 domain 2
  • Zebrafish(797187) IQ motif and Sec7 domain 2
  • Zebrafish(560461) IQ motif and Sec7 domain 2
  • naked mole-rat(101711435) IQ motif and Sec7 domain 2
  • cow(517311) IQ motif and Sec7 domain 2
  • sheep(101109678) IQ motif and Sec7 domain 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IQSEC2 antibody produced in mouse, purified immunoglobulin,
Species Reactivity
human
Application
western blot
Anti-IQSEC2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-IQSEC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Iqsec2,
Species
mouse
MISSION® esiRNA, targeting human IQSEC2,
Species
human