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ING3

inhibitor of growth family, member 3

Synonyms:
Eaf4, ING2, MEAF4, p47ING3
Species:
UniProtKB ID:
Gene ID:
  • Human(54556) Summary: The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(71777) inhibitor of growth family, member 3
  • Rat(312154) inhibitor of growth family, member 3
  • domestic guinea pig(100721269) inhibitor of growth family, member 3
  • sheep(101102722) inhibitor of growth family, member 3
  • cow(513000) inhibitor of growth family, member 3
  • dog(475299) inhibitor of growth family, member 3
  • Zebrafish(393911) inhibitor of growth family, member 3
  • naked mole-rat(101711218) inhibitor of growth family, member 3
  • domestic cat(101089592) inhibitor of growth family, member 3
  • chicken(417762) inhibitor of growth family, member 3
  • Horse(100056220) inhibitor of growth family, member 3
  • fruit fly(32853) CG6632 gene product from transcript CG6632-RA

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ING3 antibody produced in mouse, clone 2C4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-ING3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-ING3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-ING3 Antibody, clone 2A2, clone 2A2, from mouse,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ING3,
Species
human
MISSION® esiRNA, targeting mouse Ing3,
Species
mouse