IFIH1
interferon induced with helicase C domain 1
Synonyms:
Hlcd, IDDM19, MDA-5, MDA5, RLR-2
Species:
Human IFIH1 (64135), Mouse Ifih1 (71586), Rat Ifih1 (499801), naked mole-rat Ifih1 (101721395), domestic guinea pig Ifih1 (100717607), cow IFIH1 (535490), sheep IFIH1 (101106234), chicken IFIH1 (424185), dog IFIH1 (488371), domestic cat IFIH1 (101099233)
UniProtKB ID:
Gene ID:
- Human(64135) Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012]
- Mouse(71586) interferon induced with helicase C domain 1
- Rat(499801) interferon induced with helicase C domain 1
- naked mole-rat(101721395) interferon induced with helicase C domain 1
- domestic guinea pig(100717607) interferon induced with helicase C domain 1
- cow(535490) interferon induced with helicase C domain 1
- sheep(101106234) interferon induced with helicase C domain 1
- chicken(424185) interferon induced with helicase C domain 1
- dog(488371) interferon induced with helicase C domain 1
- domestic cat(101099233) interferon induced with helicase C domain 1
- Horse(100061257) interferon induced with helicase C domain 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-IFIH1 antibody produced in mouse, clone 3F6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-IFIH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-MDA5/IFIH1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Anti-IFIH1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-MDA5 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot