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HERC4

HECT and RLD domain containing E3 ubiquitin protein ligase 4

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(26091) Summary: HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]
  • Mouse(67345) hect domain and RLD 4
  • Rat(309758) HECT and RLD domain containing E3 ubiquitin protein ligase 4
  • sheep(101103532) HECT and RLD domain containing E3 ubiquitin protein ligase 4
  • dog(479225) HECT and RLD domain containing E3 ubiquitin protein ligase 4
  • chicken(423683) HECT and RLD domain containing E3 ubiquitin protein ligase 4
  • Zebrafish(557513) hect domain and RLD 4
  • naked mole-rat(101725893) HECT and RLD domain containing E3 ubiquitin protein ligase 4
  • domestic guinea pig(100717289) HECT and RLD domain containing E3 ubiquitin protein ligase 4
  • Domestic Rabbit(100348847) HECT and RLD domain containing E3 ubiquitin protein ligase 4
  • cow(533336) HECT and RLD domain containing E3 ubiquitin protein ligase 4

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-HERC4 antibody produced in mouse, clone 2G7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-HERC4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-HERC4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human HERC4,
Species
human
MISSION® esiRNA, targeting mouse Herc4,
Species
mouse