GTF2H2
general transcription factor IIH, polypeptide 2, 44kDa
Synonyms:
BTF2, BTF2P44, T-BTF2P44, TFIIH, p44
Species:
Human GTF2H2 (2966), Mouse Gtf2h2 (23894), Rat Gtf2h2 (294693), cow GTF2H2 (511829), domestic guinea pig Gtf2h2 (100733552), naked mole-rat Gtf2h2 (101705678), Zebrafish gtf2h2 (323239), chicken GTF2H2 (100858972), Thale Cress GTF2H2 (839332), dog GTF2H2 (478089) ...More
UniProtKB ID:
Gene ID:
- Human(2966) Summary: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs; however, no sequence data is currently available for the centromeric copy of the gene. [provided by RefSeq, Jul 2008]
- Mouse(23894) general transcription factor II H, polypeptide 2
- Rat(294693) general transcription factor IIH, polypeptide 2
- cow(511829) general transcription factor IIH, polypeptide 2, 44kDa
- domestic guinea pig(100733552) general transcription factor IIH, polypeptide 2, 44kDa
- naked mole-rat(101705678) general transcription factor IIH, polypeptide 2, 44kDa
- Zebrafish(323239) general transcription factor IIH, polypeptide 2
- chicken(100858972) general transcription factor IIH, polypeptide 2, 44kDa
- Thale Cress(839332) transcription initiation factor TFIIH subunit H2
- dog(478089) general transcription factor IIH, polypeptide 2, 44kDa
- domestic cat(101094730) general transcription factor IIH, polypeptide 2, 44kDa
- Horse(100073305) general transcription factor IIH, polypeptide 2, 44kDa
- sheep(101118051) general transcription factor IIH, polypeptide 2, 44kDa
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GTF2H2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-GTF2H2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-GTF2H2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
esiRNA
Product Number
Description
Species