FBXW8
F-box and WD repeat domain containing 8
Synonyms:
FBW6, FBW8, FBX29, FBXO29, FBXW6
Species:
Human FBXW8 (26259), Mouse Fbxw8 (231672), Rat Fbxw8 (304522), sheep FBXW8 (101108081), domestic guinea pig Fbxw8 (100728842), naked mole-rat Fbxw8 (101714467), Zebrafish fbxw8 (100136859), chicken FBXW8 (417024), dog FBXW8 (486288), domestic cat FBXW8 (101091406)
UniProtKB ID:
Gene ID:
- Human(26259) Summary: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(231672) F-box and WD-40 domain protein 8
- Rat(304522) F-box and WD repeat domain containing 8
- sheep(101108081) F-box and WD repeat domain containing 8
- domestic guinea pig(100728842) F-box and WD repeat domain containing 8
- naked mole-rat(101714467) F-box and WD repeat domain containing 8
- Zebrafish(100136859) F-box and WD repeat domain containing 8
- chicken(417024) F-box and WD repeat domain containing 8
- dog(486288) F-box and WD repeat domain containing 8
- domestic cat(101091406) F-box and WD repeat domain containing 8
- cow(787118) F-box and WD repeat domain containing 8
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-FBXW8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-FBXW8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry