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Merck

FBXO5

F-box protein 5

Synonyms:
EMI1, FBX5, Fbxo31
Species:
Human FBXO5 (26271), Mouse Fbxo5 (67141), Rat Fbxo5 (292263), domestic guinea pig Fbxo5 (100714021), naked mole-rat Fbxo5 (101713387), domestic cat FBXO5 (101089013), chicken FBXO5 (421642), sheep FBXO5 (101103731), Domestic Rabbit FBXO5 (100353279), dog FBXO5 (612020) ...More
UniProtKB ID:
Q9UKT4, B3KNX5, Q5TF47, Q8WV29, Q9UGC8
Gene ID:
  • Human(26271) Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Dec 2008]
  • Mouse(67141) F-box protein 5
  • Rat(292263) F-box protein 5
  • domestic guinea pig(100714021) F-box protein 5
  • naked mole-rat(101713387) F-box protein 5
  • domestic cat(101089013) F-box protein 5
  • chicken(421642) F-box protein 5
  • sheep(101103731) F-box protein 5
  • Domestic Rabbit(100353279) F-box protein 5
  • dog(612020) F-box protein 5
  • Zebrafish(445392) F-box protein 5
  • cow(515080) F-box protein 5

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2100793
Anti-FBXO5 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
HPA029048
Anti-FBXO5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EMU094261
MISSION® esiRNA, targeting mouse Fbxo5,
Species
mouse
EHU019001
MISSION® esiRNA, targeting human FBXO5,
Species
human