EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
Synonyms:
AAG1, DAP5, NAT1, P97
Species:
Human EIF4G2 (1982), Mouse Eif4g2 (13690), Rat Eif4g2 (361628), naked mole-rat Eif4g2 (101704822), dog EIF4G2 (476854), fruit fly eIF4G2 (42819), Domestic Rabbit EIF4G2 (100009236), Horse EIF4G2 (100071378), chicken EIF4G2 (395905), sheep EIF4G2 (101123232) ...More
UniProtKB ID:
Gene ID:
- Human(1982) Summary: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
- Mouse(13690) eukaryotic translation initiation factor 4, gamma 2
- Rat(361628) eukaryotic translation initiation factor 4, gamma 2
- naked mole-rat(101704822) eukaryotic translation initiation factor 4 gamma, 2
- dog(476854) eukaryotic translation initiation factor 4 gamma, 2
- fruit fly(42819) eukaryotic translation initiation factor 4G2
- Domestic Rabbit(100009236) eukaryotic translation initiation factor 4 gamma, 2
- Horse(100071378) eukaryotic translation initiation factor 4 gamma, 2
- chicken(395905) eukaryotic translation initiation factor 4 gamma, 2
- sheep(101123232) eukaryotic translation initiation factor 4 gamma, 2
- cow(286870) eukaryotic translation initiation factor 4 gamma, 2
- domestic guinea pig(100728504) eukaryotic translation initiation factor 4 gamma, 2
- domestic cat(101089295) eukaryotic translation initiation factor 4 gamma, 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-EIF4G2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-EIF4G2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-EIF4G2 antibody produced in mouse, clone 3E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-EIF4G2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
western blot
Anti-DAP-5 Antibody, serum, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot