DENND1B
DENN/MADD domain containing 1B
Synonyms:
C1ORF18, C1orf218, FAM31B
Species:
Human DENND1B (163486), Mouse Dennd1b (329260), Rat Dennd1b (289051), Horse DENND1B (100061134), domestic cat DENND1B (101096630), naked mole-rat Dennd1b (101713291), dog DENND1B (490259), chicken DENND1B (424351), Zebrafish dennd1b (560720), cow DENND1B (515939)
UniProtKB ID:
Gene ID:
- Human(163486) Summary: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]
- Mouse(329260) DENN/MADD domain containing 1B
- Rat(289051) DENN/MADD domain containing 1B
- Horse(100061134) DENN/MADD domain containing 1B
- domestic cat(101096630) DENN/MADD domain containing 1B
- naked mole-rat(101713291) DENN/MADD domain containing 1B
- dog(490259) DENN/MADD domain containing 1B
- chicken(424351) DENN/MADD domain containing 1B
- Zebrafish(560720) DENN/MADD domain containing 1B
- cow(515939) DENN/MADD domain containing 1B
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DENND1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
esiRNA
Product Number
Description
Species