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DAP3

death associated protein 3

Synonyms:
DAP-3, MRP-S29, MRPS29, bMRP-10
Species:
UniProtKB ID:
Gene ID:
  • Human(7818) Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Dec 2010]
  • Mouse(65111) death associated protein 3
  • Rat(295238) death associated protein 3
  • dog(480127) death associated protein 3
  • naked mole-rat(101724202) death associated protein 3
  • sheep(101120032) death associated protein 3
  • Zebrafish(559007) death associated protein 3
  • Domestic Rabbit(100353283) death associated protein 3
  • chicken(425065) death associated protein 3
  • cow(504320) death associated protein 3
  • domestic cat(101087963) death associated protein 3
  • domestic guinea pig(100717861) death associated protein 3

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-DAP3 antibody produced in mouse, clone 3B7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-DAP3 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-DAP3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-DAP3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human DAP3,
Species
human
MISSION® esiRNA, targeting mouse Dap3,
Species
mouse