CYTH2
cytohesin 2
Synonyms:
ARNO, CTS18, CTS18.1, PSCD2, PSCD2L, SEC7L, Sec7p-L, Sec7p-like
Species:
Human CYTH2 (9266), Mouse Cyth2 (19158), Rat Cyth2 (116692), domestic guinea pig Cyth2 (100731442), naked mole-rat Cyth2 (101725136), dog CYTH2 (476423), cow CYTH2 (768035), domestic cat CYTH2 (101089480), sheep CYTH2 (100216436), Horse CYTH2 (100053821)
UniProtKB ID:
Gene ID:
- Human(9266) Summary: The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(19158) cytohesin 2
- Rat(116692) cytohesin 2
- domestic guinea pig(100731442) cytohesin 2
- naked mole-rat(101725136) cytohesin 2
- dog(476423) cytohesin 2
- cow(768035) cytohesin 2
- domestic cat(101089480) cytohesin 2
- sheep(100216436) cytohesin 2
- Horse(100053821) cytohesin 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CYTH2 antibody produced in mouse, clone 5E11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-CYTH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Monoclonal Anti-ARNO (Cytohesin-2) antibody produced in mouse, ~2 mg/mL, clone CYT2-21, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, rat
Application
ELISA
immunocytochemistry
microarray
western blot
immunocytochemistry
microarray
western blot