CRYBB1
crystallin, beta B1
Synonyms:
CATCN3, CTRCT17
Species:
Human CRYBB1 (1414), Mouse Crybb1 (12960), Rat Crybb1 (25421), cow CRYBB1 (282205), domestic cat CRYBB1 (101084490), naked mole-rat Crybb1 (101717949), domestic guinea pig Crybb1 (100307054), Zebrafish crybb1 (114418), dog CRYBB1 (486333), chicken CRYBB1 (374000)
UniProtKB ID:
Gene ID:
- Human(1414) Summary: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, undergoes extensive cleavage at its N-terminal extension during lens maturation. It is also a member of a gene cluster with beta-A4, beta-B2, and beta-B3. [provided by RefSeq, Jul 2008]
- Mouse(12960) crystallin, beta B1
- Rat(25421) crystallin, beta B1
- cow(282205) crystallin, beta B1
- domestic cat(101084490) crystallin, beta B1
- naked mole-rat(101717949) crystallin, beta B1
- domestic guinea pig(100307054) crystallin, beta B1
- Zebrafish(114418) crystallin, beta B1
- dog(486333) crystallin, beta B1
- chicken(374000) crystallin, beta B1
- sheep(101118903) crystallin, beta B1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CRYBB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-CRYBB1 antibody produced in mouse, clone 2B2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
esiRNA
Product Number
Description
Species