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Merck

COQ2

coenzyme Q2 4-hydroxybenzoate polyprenyltransferase

Synonyms:
CL640, COQ10D1, MSA1
Species:
UniProtKB ID:
Gene ID:
  • Human(27235) Summary: This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. [provided by RefSeq, Oct 2009]
  • Mouse(71883) coenzyme Q2 homolog, prenyltransferase (yeast)
  • Rat(498332) coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
  • sheep(101109616) coenzyme Q2 homolog, prenyltransferase (yeast)
  • domestic guinea pig(100722163) coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
  • naked mole-rat(101700791) coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
  • cow(504633) coenzyme Q2 homolog, prenyltransferase (yeast)
  • Zebrafish(100037331) coenzyme Q2 homolog, prenyltransferase (yeast)
  • chicken(422605) coenzyme Q2 homolog, prenyltransferase (yeast)
  • dog(478457) coenzyme Q2 homolog, prenyltransferase (yeast)
  • domestic cat(101084704) coenzyme Q2 homolog, prenyltransferase (yeast)
  • fruit fly(40988) Coenzyme Q biosynthesis protein 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-COQ2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human COQ2,
Species
human
MISSION® esiRNA, targeting mouse Coq2,
Species
mouse