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CKMT1B

creatine kinase, mitochondrial 1B

Synonyms:
CKMT, CKMT1, UMTCK
Species:
Human CKMT1B (1159), Rat Ckmt1b (29593), dog CKMT1B (478277), domestic cat CKMT1B (101097983), Horse CKMT1B (100056283), naked mole-rat Ckmt1b (101725224), sheep CKMT1B (101108520), cow CKMT1B (281692)
UniProtKB ID:
Gene ID:
  • Human(1159) Summary: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]
  • Rat(29593) creatine kinase, mitochondrial 1B
  • dog(478277) creatine kinase, mitochondrial 1B
  • domestic cat(101097983) creatine kinase, mitochondrial 1B
  • Horse(100056283) creatine kinase, mitochondrial 1B
  • naked mole-rat(101725224) creatine kinase, mitochondrial 1B
  • sheep(101108520) creatine kinase, mitochondrial 1B
  • cow(281692) creatine kinase, mitochondrial 1B

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1403672
Monoclonal Anti-CKMT1B, (C-terminal) antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
SAB1400052
Monoclonal Anti-CKMT1B antibody produced in mouse, clone 2C8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot