Skip to Content
Merck

CHMP2B

charged multivesicular body protein 2B

Synonyms:
ALS17, CHMP2.5, DMT1, VPS2-2, VPS2B
Species:
UniProtKB ID:
Gene ID:
  • Human(25978) Summary: This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. [provided by RefSeq, Jul 2008]
  • Mouse(68942) charged multivesicular body protein 2B
  • Rat(363720) charged multivesicular body protein 2B
  • fruit fly(38599) Charged multivesicular body protein 2b
  • domestic guinea pig(100734811) charged multivesicular body protein 2B
  • naked mole-rat(101717020) charged multivesicular body protein 2B
  • sheep(101121224) charged multivesicular body protein 2B
  • dog(487675) charged multivesicular body protein 2B
  • chicken(418461) charged multivesicular body protein 2B
  • cow(615954) charged multivesicular body protein 2B
  • domestic cat(101099491) charged multivesicular body protein 2B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CHMP2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CHMP2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-CHMP2B antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-CHMP2B antibody produced in mouse, clone 2H6-1E6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Monoclonal Anti-CHMP2B antibody produced in mouse, clone M1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CHMP2B,
Species
human
MISSION® esiRNA, targeting mouse Chmp2b,
Species
mouse