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Merck

BRWD1

bromodomain and WD repeat domain containing 1

Synonyms:
C21orf107, N143, WDR9
Species:
Human BRWD1 (54014), Mouse Brwd1 (93871), Rat Brwd1 (304061), Domestic Rabbit BRWD1 (100328651), naked mole-rat Brwd1 (101714700), domestic guinea pig Brwd1 (100713169), dog BRWD1 (487764), cow BRWD1 (540661), chicken BRWD1 (418521), sheep BRWD1 (101117901)
UniProtKB ID:
Q9NSI6, C9JK25, O43721, Q5R2V0, Q5R2V1, Q6P2D1, Q8TCV3, Q96QG9
Gene ID:
  • Human(54014) Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.[provided by RefSeq, Jun 2011]
  • Mouse(93871) bromodomain and WD repeat domain containing 1
  • Rat(304061) bromodomain and WD repeat domain containing 1
  • Domestic Rabbit(100328651) bromodomain and WD repeat domain containing 1
  • naked mole-rat(101714700) bromodomain and WD repeat domain containing 1
  • domestic guinea pig(100713169) bromodomain and WD repeat domain containing 1
  • dog(487764) bromodomain and WD repeat domain containing 1
  • cow(540661) bromodomain and WD repeat domain containing 1
  • chicken(418521) bromodomain and WD repeat domain containing 1
  • sheep(101117901) bromodomain and WD repeat domain containing 1
  • Zebrafish(798858) bromodomain and WD repeat domain containing 1

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2104681
Anti-BRWD1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
HPA030945
Anti-BRWD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
HPA030943
Anti-BRWD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
HPA030944
Anti-BRWD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Proteins

Product Number
Description
Species
SRP0480
WDR9 (1308-1436) human, recombinant, expressed in E. coli, ≥82% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
EMU094301
MISSION® esiRNA, targeting mouse Brwd1,
Species
mouse
EHU083711
MISSION® esiRNA, targeting human BRWD1,
Species
human