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Merck

BRAT1

BRCA1-associated ATM activator 1

Synonyms:
BAAT1, C7orf27, RMFSL
Species:
UniProtKB ID:
Gene ID:
  • Human(221927) Summary: The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
  • Mouse(231841) BRCA1-associated ATM activator 1
  • Rat(498150) BRCA1-associated ATM activator 1
  • sheep(101111600) BRCA1-associated ATM activator 1
  • chicken(769893) BRCA1-associated ATM activator 1
  • Zebrafish(678547) BRCA1-associated ATM activator 1
  • domestic cat(101086524) BRCA1-associated ATM activator 1
  • domestic guinea pig(100731655) BRCA1-associated ATM activator 1
  • cow(532550) BRCA1-associated ATM activator 1
  • naked mole-rat(101698169) BRCA1-associated ATM activator 1
  • dog(609589) BRCA1-associated ATM activator 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-BRAT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human BRAT1,
Species
human