B4GALT7
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
Synonyms:
EDSP1, XGALT1, XGPT1
Species:
Human B4GALT7 (11285), Mouse B4galt7 (218271), Rat B4galt7 (364675), domestic guinea pig B4galt7 (100729826), cow B4GALT7 (507559), Zebrafish b4galt7 (445022), domestic cat B4GALT7 (101099172), sheep B4GALT7 (100316848), dog B4GALT7 (481445), chicken B4GALT7 (416359)
UniProtKB ID:
Gene ID:
- Human(11285) Summary: This gene is a member of the beta-1,4-galactosyltransferase (beta4GalT) family. Family members encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose. Each beta4GalT member has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus which then remains uncleaved to function as a transmembrane anchor. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein linkage (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) found in proteoglycans. This enzyme differs from other beta4GalTs because it lacks the conserved Cys residues found in beta4GalT1-beta4GalT6 and it is located in cis-Golgi instead of trans-Golgi. Mutations in this gene have been associated with the progeroid form of Ehlers-Danlos syndrome. [provided by RefSeq, Oct 2009]
- Mouse(218271) xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
- Rat(364675) xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
- domestic guinea pig(100729826) xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
- cow(507559) xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
- Zebrafish(445022) xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
- domestic cat(101099172) xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
- sheep(100316848) xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
- dog(481445) xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
- chicken(416359) xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
- naked mole-rat(101713013) xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-B4GALT7 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-B4GALT7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot