B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
Synonyms:
B3GALT3, GLCT3, GLOB, Gb4Cer, P, P1, beta3Gal-T3, galT3
Species:
Human B3GALNT1 (8706), Mouse B3galnt1 (26879), Rat B3galnt1 (310508), cow B3GALNT1 (767844), chicken B3GALNT1 (425010), sheep B3GALNT1 (101104544), dog B3GALNT1 (100683634), domestic cat B3GALNT1 (101092536), chicken B3GALNT1 (425011), domestic guinea pig B3galnt1 (100729840)
UniProtKB ID:
Gene ID:
- Human(8706) Summary: This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5' UTR have been described; they all encode the same protein. [provided by RefSeq, Jul 2008]
- Mouse(26879) UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
- Rat(310508) beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
- cow(767844) beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
- chicken(425010) beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
- sheep(101104544) beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
- dog(100683634) beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
- domestic cat(101092536) beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
- chicken(425011) beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
- domestic guinea pig(100729840) beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
- naked mole-rat(101706281) beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
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