ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
Synonyms:
ATP6G, ATP6G2, NG38, VMA10
Species:
Human ATP6V1G2 (534), Mouse Atp6v1g2 (66237), Rat Atp6v1g2 (368044), naked mole-rat Atp6v1g2 (101720978), domestic guinea pig Atp6v1g2 (100723558), sheep ATP6V1G2 (101123332), domestic cat ATP6V1G2 (101084539), cow ATP6V1G2 (514368), dog ATP6V1G2 (474840)
UniProtKB ID:
Gene ID:
- Human(534) Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described. Read-through transcription also exists between this gene and the downstream DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (DDX39B) gene. [provided by RefSeq, Feb 2011]
- Mouse(66237) ATPase, H+ transporting, lysosomal V1 subunit G2
- Rat(368044) ATPase, H+ transporting, lysosomal V1 subunit G2
- naked mole-rat(101720978) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
- domestic guinea pig(100723558) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
- sheep(101123332) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
- domestic cat(101084539) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
- cow(514368) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
- dog(474840) ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ATP6V1G2 (6-20) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
western blot
Anti-ATP6V1G2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry