ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
Synonyms:
COOL2, Cool-2, MRX46, PIXA, alpha-PIX, alphaPIX
Species:
Human ARHGEF6 (9459), Mouse Arhgef6 (73341), Rat Arhgef6 (363509), Domestic Rabbit ARHGEF6 (100358647), chicken ARHGEF6 (422247), dog ARHGEF6 (610290), domestic cat ARHGEF6 (101099030), domestic guinea pig Arhgef6 (100719019), naked mole-rat Arhgef6 (101700245), Horse ARHGEF6 (100056622) ...More
UniProtKB ID:
Gene ID:
- Human(9459) Summary: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq, Jul 2008]
- Mouse(73341) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
- Rat(363509) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
- Domestic Rabbit(100358647) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
- chicken(422247) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
- dog(610290) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
- domestic cat(101099030) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
- domestic guinea pig(100719019) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
- naked mole-rat(101700245) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
- Horse(100056622) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
- cow(533823) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
- sheep(101104043) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ARHGEF6 antibody produced in mouse, clone 2E5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
proximity ligation assay
western blot
immunoprecipitation (IP)
proximity ligation assay
western blot
Anti-ARHGEF6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Arhgef6 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
Anti-ARHGEF6, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, human, mouse, rat, rhesus macaque
Application
immunocytochemistry
western blot
western blot
Monoclonal Anti-Rac antibody produced in mouse, clone 23A8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot