AP4S1
adaptor-related protein complex 4, sigma 1 subunit
AP47B, CLA20, CLAPS4, CPSQ6, SPG52
Human AP4S1 (11154), Mouse Ap4s1 (11782), Rat Ap4s1 (366618), domestic cat AP4S1 (101086729), chicken AP4S1 (423309), naked mole-rat Ap4s1 (101699663), domestic guinea pig Ap4s1 (100713810), Zebrafish ap4s1 (368852), sheep AP4S1 (101115405), dog AP4S1 (480283)
- Human(11154) Summary: This gene encodes a member of the adaptor complexes small subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is the small subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Mutations in this gene are associated with spastic quadriplegic cerebral palsy-6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Dec 2011]
- Mouse(11782) adaptor-related protein complex AP-4, sigma 1
- Rat(366618) adaptor-related protein complex 4, sigma 1 subunit
- domestic cat(101086729) adaptor-related protein complex 4, sigma 1 subunit
- chicken(423309) adaptor-related protein complex 4, sigma 1 subunit
- naked mole-rat(101699663) adaptor-related protein complex 4, sigma 1 subunit
- domestic guinea pig(100713810) adaptor-related protein complex 4, sigma 1 subunit
- Zebrafish(368852) adaptor-related protein complex 4, sigma 1 subunit
- sheep(101115405) adaptor-related protein complex 4, sigma 1 subunit
- dog(480283) adaptor-related protein complex 4, sigma 1 subunit
- cow(618267) adaptor-related protein complex 4, sigma 1 subunit
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