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AP4S1

adaptor-related protein complex 4, sigma 1 subunit

Synonyms:
AP47B, CLA20, CLAPS4, CPSQ6, SPG52
Species:
UniProtKB ID:
Gene ID:
  • Human(11154) Summary: This gene encodes a member of the adaptor complexes small subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is the small subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Mutations in this gene are associated with spastic quadriplegic cerebral palsy-6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Dec 2011]
  • Mouse(11782) adaptor-related protein complex AP-4, sigma 1
  • Rat(366618) adaptor-related protein complex 4, sigma 1 subunit
  • domestic cat(101086729) adaptor-related protein complex 4, sigma 1 subunit
  • chicken(423309) adaptor-related protein complex 4, sigma 1 subunit
  • naked mole-rat(101699663) adaptor-related protein complex 4, sigma 1 subunit
  • domestic guinea pig(100713810) adaptor-related protein complex 4, sigma 1 subunit
  • Zebrafish(368852) adaptor-related protein complex 4, sigma 1 subunit
  • sheep(101115405) adaptor-related protein complex 4, sigma 1 subunit
  • dog(480283) adaptor-related protein complex 4, sigma 1 subunit
  • cow(618267) adaptor-related protein complex 4, sigma 1 subunit

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-AP4S1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ap4s1,
Species
mouse
MISSION® esiRNA, targeting human AP4S1,
Species
human