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ANAPC2

anaphase promoting complex subunit 2

Synonyms:
APC2, RP11-350O14.5
Species:
UniProtKB ID:
Gene ID:
  • Human(29882) Summary: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq, Jul 2008]
  • Mouse(99152) anaphase promoting complex subunit 2
  • Rat(296558) anaphase promoting complex subunit 2
  • sheep(101108299) anaphase promoting complex subunit 2
  • domestic guinea pig(100730651) anaphase promoting complex subunit 2
  • naked mole-rat(101719594) anaphase promoting complex subunit 2
  • Zebrafish(100318335) anaphase promoting complex subunit 2
  • chicken(417258) anaphase promoting complex subunit 2
  • dog(491236) anaphase promoting complex subunit 2
  • domestic cat(101082786) anaphase promoting complex subunit 2
  • cow(100336564) anaphase promoting complex subunit 2
  • cow(100337474) anaphase promoting complex subunit 2

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ANAPC2, (C-terminal) antibody produced in mouse, clone 7F2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-ANAPC2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-ANAPC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ANAPC2,
Species
human
MISSION® esiRNA, targeting mouse Anapc2,
Species
mouse