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Merck

AKAP12

A kinase (PRKA) anchor protein 12

Synonyms:
AKAP250, SSeCKS
Species:
Human AKAP12 (9590), Mouse Akap12 (83397), Rat Akap12 (83425), cow AKAP12 (513774), sheep AKAP12 (101105509), dog AKAP12 (476246), naked mole-rat Akap12 (101719181), Horse AKAP12 (100063263), domestic guinea pig Akap12 (100733313), chicken AKAP12 (421634)
UniProtKB ID:
Q02952, O00310, O00498, Q4LE68, Q5SZ80, Q5TGN1, Q68D82, Q99970
Gene ID:
  • Human(9590) Summary: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(83397) A kinase (PRKA) anchor protein (gravin) 12
  • Rat(83425) A kinase (PRKA) anchor protein 12
  • cow(513774) A kinase (PRKA) anchor protein 12
  • sheep(101105509) A kinase (PRKA) anchor protein 12
  • dog(476246) A kinase (PRKA) anchor protein 12
  • naked mole-rat(101719181) A kinase (PRKA) anchor protein 12
  • Horse(100063263) A kinase (PRKA) anchor protein 12
  • domestic guinea pig(100733313) A kinase (PRKA) anchor protein 12
  • chicken(421634) A kinase (PRKA) anchor protein 12
  • domestic cat(101083007) A kinase (PRKA) anchor protein 12

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA006344
Anti-AKAP12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
SAB4503676
Anti-AKAP12 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
HPA056230
Anti-AKAP12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
S1562
Anti-SSeCKS antibody produced in sheep, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
rat
Application
immunoprecipitation (IP)
western blot
SAB1404742
Monoclonal Anti-AKAP12, (C-terminal) antibody produced in mouse, clone 3C3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
EHU092791
MISSION® esiRNA, targeting human AKAP12,
Species
human
EMU004541
MISSION® esiRNA, targeting mouse Akap12,
Species
mouse