ACKR2
atypical chemokine receptor 2
Synonyms:
CCBP2, CCR10, CCR9, CMKBR9, D6, hD6
Species:
UniProtKB ID:
Gene ID:
- Human(1238) Summary: This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008]
- Mouse(59289) atypical chemokine receptor 2
- Rat(140473) atypical chemokine receptor 2
- cow(512583) atypical chemokine receptor 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ACKR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
esiRNA
Product Number
Description
Species