PDE3A
phosphodiesterase 3A, cGMP-inhibited
Synonyms:
CGI-PDE, CGI-PDE A, CGI-PDE-A
Species:
Human PDE3A (5139), Mouse Pde3a (54611), Rat Pde3a (50678), domestic cat PDE3A (101088586), naked mole-rat Pde3a (101704787), Domestic Rabbit PDE3A (100009330), Horse PDE3A (100034086), sheep PDE3A (101115870), Zebrafish pde3a (567051), cow PDE3A (536636) ...More
UniProtKB ID:
Gene ID:
- Human(5139) Summary: This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
- Mouse(54611) phosphodiesterase 3A, cGMP inhibited
- Rat(50678) phosphodiesterase 3A, cGMP inhibited
- domestic cat(101088586) phosphodiesterase 3A, cGMP-inhibited
- naked mole-rat(101704787) phosphodiesterase 3A, cGMP-inhibited
- Domestic Rabbit(100009330) phosphodiesterase 3A, cGMP-inhibited
- Horse(100034086) phosphodiesterase 3A, cGMP-inhibited
- sheep(101115870) phosphodiesterase 3A, cGMP-inhibited
- Zebrafish(567051) phosphodiesterase 3A, cGMP-inhibited
- cow(536636) phosphodiesterase 3A, cGMP-inhibited
- chicken(418185) phosphodiesterase 3A, cGMP-inhibited
- domestic guinea pig(100302667) phosphodiesterase 3A, cGMP inhibited
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PDE3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-PDE3A antibody produced in mouse, clone 5C12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-PDE3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Small Molecule - Inhibitor
Product Number
Description
Species