跳转至内容
Merck

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

别名:
EPND, GluN2A, NMDAR2A, NR2A
物种:
UniProtKB ID:
基因ID:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

货号
说明
物种
1,4-双(3-氨丙基)哌嗪, ≥99%,
物种
rat
右美沙芬 氢溴酸盐 一水合物, certified reference material, pharmaceutical secondary standard,
物种
human
右美沙芬 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
右美沙芬 氢溴酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
右美沙芬 氢溴酸盐, meets USP testing specifications,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
4-氨基哌啶, ,
物种
rat
盐酸氯胺酮标准液 盐酸盐 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
(±)-氯胺酮 盐酸盐, solid,
物种
human
S-(+)-Ketamine hydrochloride, ,
物种
human
红藻氨酸 一水合物, ≥99% (TLC),
物种
human, mouse, rat

Small Molecule - Antagonist

货号
说明
物种
甘氨酸, ReagentPlus®, ≥99% (HPLC),
物种
rat
甘氨酸, suitable for electrophoresis, ≥99%,
物种
rat
甘氨酸, BioUltra, for molecular biology, ≥99.0% (NT),
物种
rat
甘氨酸, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%,
物种
rat
甘氨酸, ,
物种
rat

Antibodies

货号
说明
物种反应性
应用
抗 NR2A 抗体,克隆 A12W,兔单克隆, culture supernatant, clone A12W, Upstate®,
物种反应性
mouse, rat
应用
western blot
抗-NMDAR2A抗体, Chemicon®, from rabbit,
物种反应性
fish, human, mouse, rat
应用
immunohistochemistry
immunoprecipitation (IP)

western blot
抗-NR2A抗体, Upstate®, from rabbit,
物种反应性
mouse, rat
应用
immunoprecipitation (IP)
western blot
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327-95, purified immunoglobulin,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunohistochemistry

western blot
Anti-phospho NMDAR2A (Ser1459), ,
物种反应性
human
应用
immunocytochemistry
western blot

Small Molecule - Blocker

货号
说明
物种
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
物种
human
胍丁胺 硫酸盐, ≥97%, powder,
物种
human
奥芬那君 盐酸盐, ≥98.0% (AT),
物种
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
吲哚-2-羧酸, 98%,
物种
rat, human
二苯胍, 97%,
物种
rat, mouse, human
使君子氨酸, powder,
物种
rat
Nω-硝基-L-精氨酸, ≥98% (TLC),
物种
rat, mouse, human
喷他脒 羟乙基磺酸盐, powder,
物种
human

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
1,3-二氨基丙烷, ≥99%,
物种
rat
N,N′-二甲基-1,3-丙二胺, 97%,
物种
rat
N , N , N ′,N'-四甲基-1,3-丙二胺, ≥99%,
物种
rat
1,3-二氨基-2-丙醇, 95%,
物种
rat
2,2-二甲基-1,3-丙二胺, 99%,
物种
rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GRIN2A,
物种
human
MISSION® esiRNA, targeting mouse Grin2a,
物种
mouse