SMB00289

Diallyl trisulfide

≥98% (HPLC)

• Synonym(s): Allyl trisulfide, Di-2-propenyl trisulfide
• Empirical Formula (Hill Notation): C₆H₁₀S₃
• CAS Number: 2050-87-5
• Molecular Weight: 178.34
• EC Number: 218-107-8
• MDL number: MFCD00040025
• UNSPSC Code: 12352200
• PubChem Substance ID: 329824925
• NACRES: NA.25

Properties

• assay: ≥98% (HPLC)
• form: oil
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: −20°C
• SMILES string: C=CCSSSCC=C
• InChI: 1S/C6H10S3/c1-3-5-7-9-8-6-4-2/h3-4H,1-2,5-6H2
• InChI key: UBAXRAHSPKWNCX-UHFFFAOYSA-N

Description

General description

Diallyl trisulfide (DATS) is one of the organosulfur compounds found in garlic (Allium sativum), and other Allium genera such as onions. This sulfur-rich compound is produced by the rapid disintegration of its metabolic precursor Allicin.

Application

Diallyl trisulfide (DATS) has been used to study its antimicrobial effects against Campylobacter jejuni. It has also been used to test its effect on hepatic regeneration in partial hepatectomy (PHx) rats.

Biochem/physiol Actions

Diallyl trisulfide (DATS) is a potent anti-cancer and chemopreventive agent that regulates apoptosis, metastasis, cell cycle, and angiogenesis in cancer pathways. It is also an excellent neuroprotective agent. DATS elicits antioxidant and anti-inflammatory activities against doxorubicin (DOX)-induced rats brains. It may improve glycemic control, muscle glucose utilization, and insulin secretion in streptozotocin-induced diabetic rats.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable