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S6826

Sigma-Aldrich

Stiripentol

≥98% (HPLC)

Synonym(s):

4,4-dimethyl-1-[3,4(methylenedioxy)-phenyl]-1-penten-3-ol, Diacomit

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5 MG
$81.00
25 MG
$327.60

About This Item

Empirical Formula (Hill Notation):
C14H18O3
CAS Number:
49763-96-4
Molecular Weight:
234.29
EC Number:
256-480-9
MDL number:
MFCD00869310
UNSPSC Code:
12352200
PubChem Substance ID:
329824570
NACRES:
NA.77

$81.00

List Price$90.00Save 10%
Web-Only Promotion

Available to ship onApril 29, 2025Details

Request a Bulk Order

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: ≥20 mg/mL

storage temp.

−20°C

SMILES string

CC(C)(C)C(O)\C=C\c1ccc2OCOc2c1

InChI

1S/C14H18O3/c1-14(2,3)13(15)7-5-10-4-6-11-12(8-10)17-9-16-11/h4-8,13,15H,9H2,1-3H3/b7-5+

InChI key

IBLNKMRFIPWSOY-FNORWQNLSA-N

Related Categories

Application

Stiripentol has been used in pharmacokinetic analysis[1] and as a reference standard in fluorescence spectra analysis.[2]
Stiripentol may be used in GABAA receptor-mediated cell signaling studies.

Biochem/physiol Actions

Anti-convulsant drug

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000440034
0000440032
0000440032
0000440034
0000348788

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Yushi Inoue et al.
Epilepsia, 50(11), 2362-2368 (2009-06-26)
To survey the treatment situation of Dravet syndrome in Japan and to compare this result with effectiveness of stiripentol (STP) add-on therapy in an open-label multicenter study. Medical records of patients with Dravet syndrome who visited the study institutions during
Atsushi Fujiwara et al.
Journal of anesthesia, 34(3), 373-381 (2020-03-20)
Antiepileptic drugs are used not only for the treatment of epilepsy but also for that of neuropathic pain. However, their action mechanisms have not always been well explained. Stiripentol, an effective antiepileptic drug indicated as a therapeutic for Dravet syndrome
Catherine Chiron
Developmental medicine and child neurology, 53 Suppl 2, 16-18 (2011-04-29)
Dravet syndrome is a highly pharmaco-resistant form of epilepsy. Valproate and benzodiazepines are the first-line treatment but are usually insufficient therapeutic options. Lamotrigine, carbamazepine and high doses of intravenous phenobarbital can aggravate seizures and should be avoided. Topiramate, levetiracetam, bromide
Rima Nabbout et al.
Epilepsia, 52(7), e54-e57 (2011-05-17)
We aimed to test the efficacy of ketogenic diet (KD) in patients with Dravet syndrome (DS) not satisfactorily controlled by antiepileptic drugs (AEDs). We included prospectively 15 DS patients aged >3 years with partial response to AEDs including stiripentol. All
Janet L Fisher
European journal of pharmacology, 654(2), 160-165 (2011-01-18)
Many patients with refractory epilepsy are treated with polytherapy, and nearly 15% of epilepsy patients receive two or more anti-convulsant agents. The anti-convulsant stiripentol is used as an add-on treatment for the childhood epilepsy syndrome known as severe myoclonic epilepsy
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