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P6517

Sigma-Aldrich

1,2-Distearoyl-sn-glycero-3-phosphocholine

≥99% (TLC)

Synonym(s):

PC, 1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-distearoyl, L-α-Phosphatidylcholine, distearoyl, L-β,γ-Distearoyl-α-lecithin, DSPC, PC(18:0/18:0)

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About This Item

Empirical Formula (Hill Notation):
C44H88NO8P
CAS Number:
816-94-4
Molecular Weight:
790.15
Beilstein/REAXYS Number:
3923978
EC Number:
212-440-2
MDL number:
MFCD00036905
UNSPSC Code:
12352211
PubChem Substance ID:
329820247

assay

≥99% (TLC)

form

powder

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

InChI key

NRJAVPSFFCBXDT-HUESYALOSA-N

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General description

Non-pyrogenic, well-defined liposomes, loaded with a molecule of choice, are formed by a single hydration step.

Preparation Note

A further purification by crystallization of P1138.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
087K5204
073H8386
062K1481
060H8359
045K5202

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Corrigendum to "In Vivo Characterization of Ultrasound Contrast Agents: Microbubble Spectroscopy in a Chicken Embryo" (Ultrasound Med Biol 2012;38:1608-1617).
Telli Faez et al.
Ultrasound in medicine & biology, 47(6), 1638-1638 (2021-03-19)
Ilya Skachkov et al.
PloS one, 13(9), e0204354-e0204354 (2018-09-21)
In vivo cell tracking of therapeutic, tumor, and endothelial cells is an emerging field and a promising technique for imaging cardiovascular disease and cancer development. Site-specific labeling of endothelial cells with the MRI contrast agent superparamagnetic iron oxide (SPIO) in
Corrigendum to "Non-linear Response and Viscoelastic Properties of Lipid-Coated Microbubbles: DSPC versus DPPC" (Ultrasound Med Biol 2015;41:1432-1445).
Tom van Rooij et al.
Ultrasound in medicine & biology, 47(6), 1640-1640 (2021-03-19)
Corrigendum to "Secondary Bjerknes Forces Deform Targeted Microbubbles" (Ultrasound Med Biol 2013;39:490-506).
Tom J A Kokhuis et al.
Ultrasound in medicine & biology, 47(6), 1639-1639 (2021-03-19)
Pan Li et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(2), 349-354 (2012-07-18)
Ultrasound targeted microbubble destruction (UTMD) was one of the most promising strategies to enhance drug delivery in cancer therapy. Microbubbles (MBs) serve as a vehicle to carry anti-tumor drugs and locally release them when exposed to therapeutic ultrasound, resulting in
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