Selective inhibitor of nitric oxide synthase from mouse brain.
Features and Benefits
This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
International journal of molecular sciences, 21(18) (2020-09-12)
The poly(ADP-ribose) polymerase (PARP) inhibitor PJ34 has been reported to improve endothelial dysfunction in the peripheral system. We addressed the role of PJ34 on the vascular tone and vasoreactivity during development in the mouse brain. Blood flows were measured in
Trends in neurosciences, 14(2), 60-67 (1991-02-01)
Nitric oxide (NO) is a recently discovered and highly unorthodox messenger molecule. Current evidence indicates that, in the CNS, NO is produced enzymatically in postsynaptic structures in response to activation of excitatory amino acid receptors. It then diffuses out to
American journal of physiology. Cell physiology, 311(6), C1014-C1026 (2016-10-14)
Central CO2-chemosensitive neurons in the caudal solitary complex (cSC) are stimulated not only by hypercapnic acidosis, but by hyperoxia as well. While a cellular mechanism for the CO2 response has yet to be isolated, previous data show that a redox-sensitive
American journal of physiology. Renal physiology, 313(4), F864-F873 (2017-07-07)
Via developmental programming, prenatal perturbations, such as exposure to glucocorticoids and maternal malnutrition alter kidney development and contribute to the development of hypertension. To examine the possibility that alterations in tubuloglomerular feedback (TGF) contribute to the development of hypertension in
European journal of pharmacology, 683(1-3), 166-173 (2012-03-28)
Long-term treatment with the dopamine precursor levodopa (l-DOPA) frequently induces dyskinesia in Parkinson's disease patients, which is a major complication of this therapy. Previous studies using animal models show that repeated administration of l-DOPA results in alterations of some signaling
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
![1-[2-(Trifluoromethyl)phenyl]imidazole](/deepweb/assets/sigmaaldrich/product/structures/150/780/ea7e6b25-7659-422e-868c-8df7fd70d66e/640/ea7e6b25-7659-422e-868c-8df7fd70d66e.png)
