N7769
Nivalenol from Fusarium nivale
≥98%
Synonym(s):
3α,4β,7α,15-Tetrahydroxy-12,13-epoxytrichothec-9-en-8-one
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About This Item
Empirical Formula (Hill Notation):
C15H20O7
CAS Number:
Molecular Weight:
312.32
MDL number:
UNSPSC Code:
12352200
assay
≥98%
storage temp.
2-8°C
SMILES string
CC1=C[C@H]2O[C@@H]3[C@H](O)[C@@H](O)[C@@](C)([C@]34CO4)[C@@]2(CO)[C@H](O)C1=O
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Acute Tox. 2 Dermal
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Deyu Huang et al.
Scientific reports, 7(1), 17079-17079 (2017-12-08)
Nivalenol (NIV), a type B trichothecenes commonly found in cereal crops, can cause growth impairment in animals. However, limited information about its mechanisms is available. Trichothecenes have been characterized as an inhibitor of protein synthesis and induce apoptosis in cells.
Jungkwan Lee et al.
Applied and environmental microbiology, 78(7), 2161-2167 (2012-01-31)
Fusarium graminearum (Gibberella zeae) is an important pathogen of wheat, maize, barley, and rice in South Korea, and harvested grain often is contaminated with trichothecenes such as deoxynivalenol and nivalenol. In this study, we examined 568 isolates of F. graminearum
Tadahiro Suzuki et al.
Journal of agricultural and food chemistry, 60(37), 9519-9527 (2012-08-18)
Type B trichothecenes, deoxynivalenol (DON) and nivalenol (NIV), are secondary metabolites of Fusarium species and are major pollutants in food and feed products. Recently, the production trend of their derivatives, 3-acetyldeoxynivalenol (3-AcDON), 15-acetyldeoxynivalenol (15-AcDON), and 4-acetylnivalenol (4-AcNIV or fusarenon-X), has
E D Van Asselt et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 29(10), 1556-1565 (2012-06-30)
Mycotoxins are secondary metabolites produced by fungi that can cause adverse health effects. Due to climate change, temperatures are expected to rise and changes in rainfall patterns are foreseen. These developments may increase fungal occurrence and mycotoxin concentrations in maize.
G Barros et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 29(2), 293-303 (2011-05-21)
Soybean (Glycine max L.), the main source of protein throughout the world, is used both as a food and a feedstuff. Currently, limited information about the occurrence of Fusarium species and mycotoxins in soybean grain and by-products is available. The
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