MAK110
MTP Activity Assay Kit
Supplied by Roar Biomedical, Inc.
Synonym(s):
MTTP Activity Assay Kit, Microsomal triglyceride transfer protein activity assay kit
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1 KIT
$747.00
About This Item
UNSPSC Code:
12161503
NACRES:
NA.84
Recommended Products
usage
sufficient for 100 fluorometric tests
application(s)
pharmaceutical
detection method
fluorometric
relevant disease(s)
cardiovascular diseases
storage temp.
2-8°C
Gene Information
human ... MTTP(4547)
General description
Microsomal triglyceride transfer protein (MTP), a membrane-bound protein present in the liver, plays an important role in the assembly and secretion of very low density lipoprotein (VLDL).[1] MTP is also necessary for assembly and secretion of chylomicrons by the intestine.[1] This protein facilitates the transfer of triglyceride (TG), cholesteryl ester (CE) and phosphatidylcholine (PC) between phospholipid surfaces. Mutation in the MTP gene leads to abetalipoproteinemia.[1][2]
Application
MTP Activity Assay Kit has been used to measure the activity of microsomal triglyceride transfer protein (MTP).[3]
Features and Benefits
Compatible with high-throughput handling systems.
Suitability
Suitable for measuring microsomal [triglyceride] transfer protein (MTP) activity in cell lysates or tissue homogenates, or for screening MTP activity inhibitors.
Principle
The MTP Activity Assay Kit is a sensitive, homogeneous fluorometric assay useful for continuous measurement of MTP activity in cell lysate or tissue homogenate. This kit includes proprietary substrates that enable the detection of MTP-mediated transfer of neutral lipid. The transfer activity results in an increase in fluorescence intensity (λEx=465 nm/λEm=535 nm).
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Storage Class
10 - Combustible liquids
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