H8664

Steviol hydrate

≥98% (HPLC), powder

• Synonym(s): (4α)-13-Hydroxykaur-16-en-18-oic acid hydrate
• Empirical Formula (Hill Notation): C₂₀H₃₀O₃ · xH₂O
• CAS Number: 471-80-7
• Molecular Weight: 318.45 (anhydrous basis)
• MDL number: MFCD20441965
• UNSPSC Code: 12161501
• PubChem Substance ID: 329815252
• NACRES: NA.77

Properties

• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: DMSO: >10 mg/mL
• storage temp.: 2-8°C
• SMILES string: O.C[C@@]12CCC[C@](C)([C@H]1CC[C@]34CC(=C)[C@](O)(CC[C@@H]23)C4)C(O)=O
• InChI: 1S/C20H30O3.H2O/c1-13-11-19-9-5-14-17(2,7-4-8-18(14,3)16(21)22)15(19)6-10-20(13,23)12-19;/h14-15,23H,1,4-12H2,2-3H3,(H,21,22);1H2/t14-,15-,17+,18+,19+,20-;/m0./s1
• InChI key: SGPAFVVDOPSBEU-CRRYNOPCSA-N

Description

Biochem/physiol Actions

Steviol is an inhibitor of hOAT1 and hOAT3 organic anion transporters. Human organic anion transporter hOAT1 belongs to a superfamily of organic anion transporters, which play critical roles in the body disposition of clinically important drugs including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. Steviol is a useful tool for studying renal drug clearance.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable