D2510

Deoxycholic acid

≥98% (HPLC)

• Synonym(s): 3α,12α-Dihydroxy-5β-cholanic acid, 7-Deoxycholic acid, Desoxycholic acid
• Empirical Formula (Hill Notation): C₂₄H₄₀O₄
• CAS Number: 83-44-3
• Molecular Weight: 392.57
• Beilstein/REAXYS Number: 3219882
• EC Number: 201-478-5
• MDL number: MFCD00003673
• UNSPSC Code: 12161900
• PubChem Substance ID: 24893692
• NACRES: NA.25

Properties

• biological source: bovine bile (ex gall bladder)
• Quality Level: 200
• description: anionic
• assay: ≥98% (HPLC)
• form: powder
• mol wt: 392.57 g/mol
• mp: 171-174 °C (lit.)
• functional group: carboxylic acid
• shipped in: ambient
• storage temp.: room temp
• SMILES string: C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
• InChI: 1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1
• InChI key: KXGVEGMKQFWNSR-LLQZFEROSA-N
• Gene Information: human ... ATIC(471)

Description

General description

Deoxycholic acid is a proinflammatory agent.

Application

Deoxycholic acid has been used in a study to assess a pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment. It has also been used in a study to investigate dose-dependent anti-inflammatory effect of ursodeoxycholic acid in experimental colitis.

Biochem/physiol Actions

Bile Acid

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves