C9755

Cytidine 5′-diphosphate sodium salt hydrate

from yeast, ≥95%

• Synonym(s): CDP sodium salt hydrate
• Empirical Formula (Hill Notation): C₉H₁₅N₃O₁₁P₂
• Molecular Weight: 403.18
• MDL number: MFCD00069770
• UNSPSC Code: 41106305
• PubChem Substance ID: 24893191
• NACRES: NA.51

Properties

• biological source: yeast
• Quality Level: 200
• assay: ≥95%
• form: powder
• storage temp.: −20°C
• SMILES string: [Na].NC1=NC(=O)N(C=C1)C2OC(COP(O)(=O)OP(O)(O)=O)C(O)C2O
• InChI: 1S/C9H15N3O11P2.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H2,10,11,15)(H2,16,17,18);;
• InChI key: MAGSIBHRUIBONY-UHFFFAOYSA-N

Description

General description

Cytidine 5′-diphosphate (CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK).[1] CTP synthetase catalyzes the conversion of CTP to CDP intermediates like CDP-diacylglycerol, CDP-choline and CDP-ethanolamine for phospholipid biosynthesis.[2]

Application

Cytidine 5′-diphosphate sodium salt hydrate has been used:

• as a substrate in nucleoside diphosphatase (NDPase) enzyme histochemistry assay of gold fish eye sections[3]
• in ribonucleotide reductase assay
• dCDP formation assay.[4]

Biochem/physiol Actions

Cytidine 5′-diphosphate (CDP) is used as a substrate of nucleoside diphosphatase kinase[3] to produce CTP for supporting DNA and RNA biosynthesis and of ribonucleotide reductase to product dCMP.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: Eyeshields, Gloves, type N95 (US)