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C9275

Sigma-Aldrich

Calcium Ionophore A23187 hemicalcium salt

powder

Synonym(s):

A23187 hemicalcium salt, Antibiotic A 23187 hemicalcium salt, Calcimycin hemicalcium salt, Calimycin hemicalcium salt

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About This Item

Empirical Formula (Hill Notation):
C29H36Ca0.5N3O6
CAS Number:
59450-89-4
Molecular Weight:
542.65
Beilstein/REAXYS Number:
6765084
MDL number:
MFCD00077678
UNSPSC Code:
12352200
PubChem Substance ID:
24893145
NACRES:
NA.32

sterility

non-sterile

Quality Level

200

form

powder

color

yellow

solubility

DMSO: soluble
ethanol: soluble

antibiotic activity spectrum

Gram-positive bacteria
fungi

mode of action

cell membrane | interferes

storage temp.

2-8°C

SMILES string

CNc1ccc2oc(C[C@H]3O[C@@]4(CC[C@H]3C)O[C@@H]([C@H](C)C[C@H]4C)[C@H](C)C(=O)c5ccc[nH]5)nc2c1C(=O)O[Ca]OC(=O)c6c(NC)ccc7oc(C[C@H]8O[C@@]9(CC[C@H]8C)O[C@@H]([C@H](C)C[C@H]9C)[C@H](C)C(=O)c%10ccc[nH]%10)nc67

InChI

1S/2C29H37N3O6.Ca/c2*1-15-10-11-29(17(3)13-16(2)27(38-29)18(4)26(33)20-7-6-12-31-20)37-22(15)14-23-32-25-21(36-23)9-8-19(30-5)24(25)28(34)35;/h2*6-9,12,15-18,22,27,30-31H,10-11,13-14H2,1-5H3,(H,34,35);/q;;+2/p-2/t15-,16-,17-,18-,22-,27+,29?;15-,16-,17-,18-,22-,27+,29+;/m11./s1

InChI key

LAQWEYASNNRUGY-PLYBNSMSSA-L

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Application

Ionophore highly selective for Ca2+. Potentiates responses to NMDA but not quisqualate. In cell culture, stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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