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C9008

Sigma-Aldrich

p-Coumaric acid

≥98% purity (HPLC), powder

Synonym(s):

trans-4-Hydroxycinnamic acid

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1 G
$14.67
5 G
$38.79
10 G
$72.80
25 G
$118.80

About This Item

Linear Formula:
HOC6H4CH=CHCO2H
CAS Number:
501-98-4
Molecular Weight:
164.16
Beilstein/REAXYS Number:
2207383
MDL number:
MFCD00004399
UNSPSC Code:
12171500
PubChem Substance ID:
24893127
NACRES:
NA.47

$14.67

List Price$16.30Save 10%
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Product Name

p-Coumaric acid, ≥98.0% (HPLC)

Quality Level

200

assay

≥98.0% (HPLC)

form

powder

technique(s)

titration: suitable

color

white to yellow

mp

214 °C (dec.) (lit.)

solubility

ethanol: 50 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

OC(=O)\C=C\c1ccc(O)cc1

InChI

1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3+

InChI key

NGSWKAQJJWESNS-ZZXKWVIFSA-N

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Application

p-Coumaric acid has been used as a component of chemiluminescent substrate for protein detection in western blotting.[1][2][3]

Biochem/physiol Actions

Hydroxycinnamic acid found in many fruits and vegetables.
In western blot, p-coumaric is also used as an enhancer in chemiluminescent substrate.[4]

Other Notes

Predominantly trans isomer.

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Description
Pricing

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM2882
BCCL6658
BCCL0049
BCCJ1325
BCCG8417

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A cost effective non-commercial ECL-solution for Western blot detections yielding strong signals and low background.
Haan C and Behrmann I
Journal of Immunological Methods, 318, 11-11 (2007)
Inflammation triggers high mobility group box 1 (HMGB1) secretion in adipose tissue, a potential link to obesity.
Gunasekaran MK, et al.
Cytokine, 64, 103-111 (2013)
p-Coumaric acid kills bacteria through dual damage mechanisms.
Zaixiang L, et al.
Food Control, 25, 550-554 (2012)
TGF-beta receptor levels regulate the specificity of signaling pathway activation and biological effects of TGF-beta.
Rojas A, et al.
Biochimica et Biophysica Acta, 1793, 1165-1173 (2009)
p-Coumaric acid, a common dietary phenol, inhibits platelet activity in vitro and in vivo.
Luceri C, et al.
The British Journal of Nutrition, 97, 458-463 (2007)
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Protocols

HPLC Analysis of Polyphenols in Nero d'Avola Red Wine on Discovery® HS C18 (UV 280 nm)

HPLC Analysis of Polyphenols in Nero d'Avola Red Wine on Discovery® HS C18 (UV 280 nm)

HPLC Analysis of Flavonoids on Ascentis® RP-Amide

Protocol for HPLC Analysis of Flavonoids on Ascentis® RP-Amide

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