C3519
Cephaloridine
Synonym(s):
N-(7-[2′-Thienylacetamidoceph-3-ylmethyl])pyridinium 2-carboxylate
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About This Item
Empirical Formula (Hill Notation):
C19H17N3O4S2
CAS Number:
Molecular Weight:
415.49
EC Number:
MDL number:
UNSPSC Code:
12352200
Storage temp.
2-8°C
SMILES string
[O-]C(=O)C1=C(CS[C@@H]2[C@H](NC(=O)Cc3cccs3)C(=O)N12)C[n+]4ccccc4
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Substrates
Substrate for cephalosporinase, although the activity is only 20-30% of that obtained using cephalosporin C.
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Lei Diao et al.
Molecular pharmaceutics, 7(6), 2120-2131 (2010-09-14)
Organic cation/carnitine transporter (OCTN2; SLC22A5) is an important transporter for L-carnitine homeostasis, but can be inhibited by drugs, which may cause L-carnitine deficiency and possibly other OCTN2-mediated drug-drug interactions. One objective was to develop a quantitative structure-activity relationship (QSAR) of
Michael E Pichichero et al.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 136(3), 340-347 (2007-02-27)
Recent analysis of clinical data and a clearer understanding of the role of chemical structure in the development of cross-reactivity indicate that the increased risk of an allergic reaction to a cephalosporin in penicillin-allergic patients is smaller than previously postulated.
C Cojocel et al.
Archives of toxicology, 78(9), 525-532 (2004-04-09)
In the present study, the effects of resveratrol on 6-hydroxydopamine (6-OHDA)-induced p-aminohippurate (PAH) transport impairment were investigated in vitro using rat renal cortical slices. Cisplatin and cephaloridine (CPH), known nephrotoxins, were used as positive controls. In one series of experiments
The growth rate of Mycobacterium smegmatis depends on sufficient porin-mediated influx of nutrients.
Joachim Stephan et al.
Molecular microbiology, 58(3), 714-730 (2005-10-22)
Mycobacteria have a unique outer membrane (OM) that is thicker than any other known biological membrane. Nutrients cross this permeability barrier by diffusion through porins. MspA is the major porin of Mycobacterium smegmatis. In this study we showed that three
Yuka Kohda et al.
Biochemical pharmacology, 64(3), 543-549 (2002-07-31)
The development of nephrotoxicity induced by cephaloridine (CER) has been reported to be due to reactive oxygen species (ROS). Protein kinase C (PKC) has been suggested to modulate the generation of ROS. We investigated the possible participation of ROS generation
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