C1181
Carboxyethyl-γ-aminobutyric acid
≥80% (HPLC)
Synonym(s):
CEGABA
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assay
≥80% (HPLC)
SMILES string
OC(=O)CCCNCCC(O)=O
InChI
1S/C7H13NO4/c9-6(10)2-1-4-8-5-3-7(11)12/h8H,1-5H2,(H,9,10)(H,11,12)
InChI key
SRGQUICKDUQCKO-UHFFFAOYSA-N
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Biochem/physiol Actions
Cell growth promoter
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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Neuroscience letters, 77(3), 308-310 (1987-06-26)
The di-carboxylated derivative of spermidine, N-carboxyethyl gamma-aminobutyric acid (CEGABA) has been identified in bovine brain and human cerebrospinal fluid by HPLC. This discovery strongly suggests the existence of a metabolic pathway connecting polyamines and GABA via putreanine and CEGABA through
Biochemical and biophysical research communications, 150(3), 931-936 (1988-02-15)
A polyamine derivative, carboxyethyl - Aminobutyric Acid (CEGABA), induces the formation of a large number of Epstein-Barr Virus (EBV) transformed lymphocytes, when added to the culture medium immediately after EBV infection. However, CEGABA shows only a moderate effect on the
Archives of dermatological research, 311(6), 491-497 (2019-05-16)
Cosmeceuticals are cosmetics formulated using compounds with medical-like benefits. Though the antiaging effect of carboxyethyl aminobutyric acid (CEGABA) has been discussed, its action mechanism in cosmeceuticals remains unclear. This study assessed the in vitro efficacy and safety of CEGABA. NHI-3T3
Il Farmaco; edizione scientifica, 43(4), 363-372 (1988-04-01)
The central effects of carboxyethyl-gamma-aminobutyric acid (CEGABA) have been studied both in rabbits and in the guinea pig myoclonus model. This drug caused EEG synchronization and behavioural sedation both after intravenous (i.v.) and intracerebroventricular (i.c.v.) administration in a dose-dependent manner
Pharmacological effects of CEGABA, a new aminoacid occurring in mammalian brain.
Il Farmaco; edizione scientifica, 42(1), 77-79 (1987-01-01)
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